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1.
Blood Cells Mol Dis ; 55(1): 68-70, 2015 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-25976470

RESUMO

BACKGROUND: Radioactive synoviorthesis was carried out by an injection of radioactive materials into the joint that has been known as a successful alternative treatment to invasive surgical synovectomy. This study was designed to evaluate short-term and long-term results and complications of radioactive synovectomy of hemophilic arthropathy using radioactive phosphorus. MATERIALS AND METHODS: This study was conducted on 40 patients with hemophilic arthropathy. After obtaining clotting factors, the intra-articular injections of radioactive phosphorus were done. Thirteen patients were evaluated during 36 months (short-term follow-up) and 27 patients were followed up for more than 36 months (long-term follow-up). Patients were evaluated for hemarthrosis, factor consumption per month, joint range of motion (ROM) and clinical and radiological involvement grade. RESULTS: The patients mean age was 22.9 ± 6.6 and there were 38 men and 2 women. Consumption of clotting factors was significantly reduced in the short-term follow-up of patients (p < 0.05), but there was no significant difference in the long-term follow-up (p > 0.05). ROM decreased significantly in the long-term follow-up (p < 0.05). Radiologic evaluation showed significantly increased involvement in their joints (p < 0.05). CONCLUSION: Using radioactive synoviorthesis led in decreased consumption of clotting factors and the hemarthrosis incidence in short term but it did not have significant impact on clinical situation (ROM) and radiological findings of hemophilic patients in long-term follow-up.


Assuntos
Hemartrose/terapia , Hemofilia A/terapia , Radioisótopos de Fósforo/uso terapêutico , Técnicas de Ablação , Adolescente , Adulto , Fatores de Coagulação Sanguínea/uso terapêutico , Feminino , Seguimentos , Hemartrose/complicações , Hemartrose/patologia , Hemartrose/fisiopatologia , Hemofilia A/complicações , Hemofilia A/patologia , Hemofilia A/fisiopatologia , Humanos , Injeções Intra-Articulares , Articulações/patologia , Articulações/fisiopatologia , Articulações/efeitos da radiação , Masculino , Amplitude de Movimento Articular/efeitos da radiação , Membrana Sinovial/patologia , Membrana Sinovial/fisiopatologia , Membrana Sinovial/efeitos da radiação , Fatores de Tempo
2.
Acta Med Iran ; 50(7): 463-7, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-22930377

RESUMO

Septic arthritis of the hip in children has multiple sequelae and may result in severe disability. Significant morbidity can be prevented by early recognition and treatment. The authors reviewed 13 children with 14 hips with sequelae of septic arthritis of the hip. All of children had history of hip septic arthritis before age of 4 years. Six were male subjects, and 7 were female subjects. We evaluated the history, clinical findings and radiographs of all children who had been treated at the Imam Khomeini hospital between 1986 and 2001 for septic arthritis of the hip. Final results of operations in patients include range of motion, presence or absence pain, joint stability, limb-length discrepancy were assessed. Three hips had mild pain in usual daily activities and one patient with cerebral palsy experienced hip instability. Most of patients (80%) had flexion contracture about 10-15 degrees .Final results showed average limb length discrepancy was about 2.8 cm. Septic arthritis of the hip in children may result in a spectrum of residual problems and the significant complications can be averted by early detection and treatment. Treatment in younger age cause better outcome.


Assuntos
Artrite Infecciosa/fisiopatologia , Quadril/patologia , Artrite Infecciosa/cirurgia , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Masculino
3.
Acta Med Iran ; 50(6): 439-43, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-22837124

RESUMO

Hutchinson-Gilford progeria syndrome (HGPS) is a rare premature ageing disorder that is characterized by accelerated degenerative changes of the cutaneous, musculoskeletal and cardiovascular systems. Mean age at diagnosis is 2.9 years and generally leading to death at approximately 13 years of age due to myocardial infarction or stroke. Orthopedic manifestations of HGPS are multiple and shoulder dislocation is a rare skeletal trauma in progeria syndrome. Our patient had simultaneous shoulder and hip dislocation associated with a low energy trauma. This subject has not been reported. Treatment accomplished as close reduction under general anesthesia and immobilization.


Assuntos
Luxação do Quadril/etiologia , Progéria/complicações , Luxação do Ombro/etiologia , Criança , Feminino , Humanos
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